BDBM50477448 CHEMBL247932
SMILES: COc1cc(\C=C\c2cccc(\C=C\c3ccc(N(C)C)c(OC)c3)c2)ccc1N(C)C
InChI Key: InChIKey=WSRSVPOCZJUQPX-DCIPZJNNSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM50477448 (CHEMBL247932) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology Curated by ChEMBL | Assay Description Inhibition of amyloid beta fibril aggregation (unknown origin) by thioflavin T fluorescence method | Bioorg Med Chem Lett 23: 3467-9 (2013) Article DOI: 10.1016/j.bmcl.2013.02.104 BindingDB Entry DOI: 10.7270/Q200050P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM50477448 (CHEMBL247932) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology Curated by ChEMBL | Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay | Bioorg Med Chem Lett 17: 1466-70 (2007) Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S | |||||||||||
More data for this Ligand-Target Pair |