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SMILES: Cc1cc(ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cc(Br)cc(c1)C(F)(F)F)S(N)(=O)=O

InChI Key: InChIKey=BPPUZZNZBFGNFL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50478052   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase protein


(Human immunodeficiency virus 1)		BDBM50478052
PNG
(CHEMBL382630)
Show SMILES Cc1cc(ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cc(Br)cc(c1)C(F)(F)F)S(N)(=O)=O
Show InChI InChI=1S/C23H17BrClF3N2O5S/c1-12-6-17(36(29,33)34)3-4-19(12)30-21(31)11-35-20-5-2-16(25)10-18(20)22(32)13-7-14(23(26,27)28)9-15(24)8-13/h2-10H,11H2,1H3,(H,30,31)(H2,29,33,34)
PDB
MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 93n/an/an/an/an/an/a



Korea Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assay

Bioorg Med Chem Lett 18: 1181-94 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.134
BindingDB Entry DOI: 10.7270/Q2NS0XPK
More data for this
Ligand-Target Pair