BDBM50479332 CHEMBL518264

SMILES: Cc1cc(=O)oc2ccc(OCC(O)CN3CCCCC3)cc12

InChI Key: InChIKey=AEMRYWAFELZCQN-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50479332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50479332 (CHEMBL518264) Show SMILES Cc1cc(=O)oc2ccc(OCC(O)CN3CCCCC3)cc12 Show InChI InChI=1S/C18H23NO4/c1-13-9-18(21)23-17-6-5-15(10-16(13)17)22-12-14(20)11-19-7-3-2-4-8-19/h5-6,9-10,14,20H,2-4,7-8,11-12H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 0.1 mg/ml				Bioorg Med Chem 16: 9009-17 (2008) Article DOI: 10.1016/j.bmc.2008.08.039 BindingDB Entry DOI: 10.7270/Q2PR7ZSZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50479332 (CHEMBL518264) Show SMILES Cc1cc(=O)oc2ccc(OCC(O)CN3CCCCC3)cc12 Show InChI InChI=1S/C18H23NO4/c1-13-9-18(21)23-17-6-5-15(10-16(13)17)22-12-14(20)11-19-7-3-2-4-8-19/h5-6,9-10,14,20H,2-4,7-8,11-12H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.04E+4	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 0.5 mg/ml				Bioorg Med Chem 16: 9009-17 (2008) Article DOI: 10.1016/j.bmc.2008.08.039 BindingDB Entry DOI: 10.7270/Q2PR7ZSZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50479332 (CHEMBL518264) Show SMILES Cc1cc(=O)oc2ccc(OCC(O)CN3CCCCC3)cc12 Show InChI InChI=1S/C18H23NO4/c1-13-9-18(21)23-17-6-5-15(10-16(13)17)22-12-14(20)11-19-7-3-2-4-8-19/h5-6,9-10,14,20H,2-4,7-8,11-12H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.61E+4	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 1.0 mg/ml				Bioorg Med Chem 16: 9009-17 (2008) Article DOI: 10.1016/j.bmc.2008.08.039 BindingDB Entry DOI: 10.7270/Q2PR7ZSZ
					More data for this Ligand-Target Pair