BDBM50479433 CHEMBL451792

SMILES: CC[C@H](CO)Nc1nc(NCc2cccc(c2)-c2cccnc2)c2ncn(C(C)C)c2n1

InChI Key: InChIKey=ZWUPUXULZQIENS-HXUWFJFHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50479433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 (Sus scrofa)	BDBM50479433 (CHEMBL451792) Show SMILES CC[C@H](CO)Nc1nc(NCc2cccc(c2)-c2cccnc2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C24H29N7O/c1-4-20(14-32)28-24-29-22(21-23(30-24)31(15-27-21)16(2)3)26-12-17-7-5-8-18(11-17)19-9-6-10-25-13-19/h5-11,13,15-16,20,32H,4,12,14H2,1-3H3,(H2,26,28,29,30)/t20-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universite Paris-Descartes Curated by ChEMBL					Assay Description Inhibition of pig brain GSK3alpha/beta				J Med Chem 51: 5229-42 (2008) Article DOI: 10.1021/jm800109e BindingDB Entry DOI: 10.7270/Q2DB84PF
					More data for this Ligand-Target Pair