BDBM50479440 CHEMBL518014

SMILES: CC[C@H](CO)Nc1nc(Nc2cccc(c2)-c2cccnc2)c2ncn(C(C)C)c2n1

InChI Key: InChIKey=GGGDZMUVJAUUIX-GOSISDBHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50479440   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 (Sus scrofa)	BDBM50479440 (CHEMBL518014) Show SMILES CC[C@H](CO)Nc1nc(Nc2cccc(c2)-c2cccnc2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C23H27N7O/c1-4-18(13-31)27-23-28-21(20-22(29-23)30(14-25-20)15(2)3)26-19-9-5-7-16(11-19)17-8-6-10-24-12-17/h5-12,14-15,18,31H,4,13H2,1-3H3,(H2,26,27,28,29)/t18-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universite Paris-Descartes Curated by ChEMBL					Assay Description Inhibition of pig brain GSK3alpha/beta				J Med Chem 51: 5229-42 (2008) Article DOI: 10.1021/jm800109e BindingDB Entry DOI: 10.7270/Q2DB84PF
					More data for this Ligand-Target Pair