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SMILES: CCOC(=O)c1c(C)n[nH]c1N\N=C\c1ccc2[nH]ccc2c1

InChI Key: InChIKey=LQDMOOMLIOLHIB-GIJQJNRQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50479514   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50479514
PNG
(CHEMBL454390)
Show SMILES CCOC(=O)c1c(C)n[nH]c1N\N=C\c1ccc2[nH]ccc2c1
Show InChI InChI=1S/C16H17N5O2/c1-3-23-16(22)14-10(2)19-21-15(14)20-18-9-11-4-5-13-12(8-11)6-7-17-13/h4-9,17H,3H2,1-2H3,(H2,19,20,21)/b18-9+
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PC cid
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PubMed
n/an/a 1.15E+4n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of Aurora kinase A T288D mutant expressed in Escherichia coli BL21 DE3

J Med Chem 52: 1050-62 (2009)


Article DOI: 10.1021/jm801270e
BindingDB Entry DOI: 10.7270/Q27M0BQJ
More data for this
Ligand-Target Pair