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SMILES: CNc1ccc(cc1)-c1nc2cc(O)ccc2s1

InChI Key: InChIKey=FOHCYFXGWJQKQP-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50480216   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50480216
PNG
(CHEMBL503833)
Show SMILES CNc1ccc(cc1)-c1nc2cc(O)ccc2s1
Show InChI InChI=1S/C14H12N2OS/c1-15-10-4-2-9(3-5-10)14-16-12-8-11(17)6-7-13(12)18-14/h2-8,15,17H,1H3
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 12n/an/an/an/an/an/an/an/a



K.U. Leuven

Curated by ChEMBL


Assay Description
Displacement of [125I]IMPY from beta-amyloid plaques in brain homogenate of patient with Alzheimer's disease by gamma counting

Eur J Med Chem 44: 1415-26 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.038
BindingDB Entry DOI: 10.7270/Q25H7K2X
More data for this
Ligand-Target Pair