BindingDB logo
myBDB logout

null

SMILES: Cc1ccc2C(=O)N(CCOC(=S)N(C(=O)c3ccc(Cl)cc3)c3ccc(cc3)[N+]([O-])=O)C(=O)c2c1

InChI Key: InChIKey=QNKOLGNMGGVARI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50480227   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50480227
PNG
(CHEMBL520032)
Show SMILES Cc1ccc2C(=O)N(CCOC(=S)N(C(=O)c3ccc(Cl)cc3)c3ccc(cc3)[N+]([O-])=O)C(=O)c2c1
Show InChI InChI=1S/C25H18ClN3O6S/c1-15-2-11-20-21(14-15)24(32)27(23(20)31)12-13-35-25(36)28(18-7-9-19(10-8-18)29(33)34)22(30)16-3-5-17(26)6-4-16/h2-11,14H,12-13H2,1H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Universit£ di Genova

Curated by ChEMBL


Assay Description
Inhibition of wild-type HIV1 reverse transcriptase

Eur J Med Chem 44: 2190-201 (2009)


Article DOI: 10.1016/j.ejmech.2008.10.032
BindingDB Entry DOI: 10.7270/Q2X069TR
More data for this
Ligand-Target Pair