BDBM50480841 CHEBI:1263::CHEMBL584140
SMILES: Nc1nc(SCCc2ccccc2)nc2sc3CCCCc3c12
InChI Key: InChIKey=SGJOGZCAZRQAMZ-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50480841![]() (CHEBI:1263 | CHEMBL584140) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Modulation of P-gp overexpressed in human A2780 cells assessed as daunorubicin accumulation preincubated 15 mins prior to daunorubicin addition measu... | Bioorg Med Chem Lett 19: 6102-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.023 BindingDB Entry DOI: 10.7270/Q2GM8B44 | |||||||||||
More data for this Ligand-Target Pair |