BDBM50480848 CHEMBL573943

SMILES: CCOC(=O)CSc1nc(N)c2c(C)c(C)sc2n1

InChI Key: InChIKey=MTIJJOSOEBIMHV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50480848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50480848 (CHEMBL573943) Show SMILES CCOC(=O)CSc1nc(N)c2c(C)c(C)sc2n1 Show InChI InChI=1S/C12H15N3O2S2/c1-4-17-8(16)5-18-12-14-10(13)9-6(2)7(3)19-11(9)15-12/h4-5H2,1-3H3,(H2,13,14,15)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Modulation of P-gp overexpressed in human A2780 cells assessed as daunorubicin accumulation preincubated 15 mins prior to daunorubicin addition measu...				Bioorg Med Chem Lett 19: 6102-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.023 BindingDB Entry DOI: 10.7270/Q2GM8B44
					More data for this Ligand-Target Pair