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SMILES: COc1cc(CCC(=O)Nc2ccc(cc2)C(=O)NO)ccc1OCc1cccc(C)c1

InChI Key: InChIKey=TUIHPOJHPHHVOK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481006   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1/2


(Homo sapiens (Human))		BDBM50481006
PNG
(CHEMBL570492)
Show SMILES COc1cc(CCC(=O)Nc2ccc(cc2)C(=O)NO)ccc1OCc1cccc(C)c1
Show InChI InChI=1S/C25H26N2O5/c1-17-4-3-5-19(14-17)16-32-22-12-6-18(15-23(22)31-2)7-13-24(28)26-21-10-8-20(9-11-21)25(29)27-30/h3-6,8-12,14-15,30H,7,13,16H2,1-2H3,(H,26,28)(H,27,29)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetry

Eur J Med Chem 44: 4470-6 (2009)


Article DOI: 10.1016/j.ejmech.2009.06.010
BindingDB Entry DOI: 10.7270/Q2P55RB1
More data for this
Ligand-Target Pair