BDBM50481012 CHEMBL570499

SMILES: COc1cc(CCC(=O)Nc2ccc(cc2)C(=O)NO)ccc1OCc1ccccc1

InChI Key: InChIKey=GRVHNZVEVOBCFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2 (Homo sapiens (Human))	BDBM50481012 (CHEMBL570499) Show SMILES COc1cc(CCC(=O)Nc2ccc(cc2)C(=O)NO)ccc1OCc1ccccc1 Show InChI InChI=1S/C24H24N2O5/c1-30-22-15-17(7-13-21(22)31-16-18-5-3-2-4-6-18)8-14-23(27)25-20-11-9-19(10-12-20)24(28)26-29/h2-7,9-13,15,29H,8,14,16H2,1H3,(H,25,27)(H,26,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetry				Eur J Med Chem 44: 4470-6 (2009) Article DOI: 10.1016/j.ejmech.2009.06.010 BindingDB Entry DOI: 10.7270/Q2P55RB1
					More data for this Ligand-Target Pair