BDBM50481310 CHEMBL603211

SMILES: Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(C#N)c(C)cc2o1

InChI Key: InChIKey=WJTCUVFUWXDBJQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Choline/ethanolaminephosphotransferase 1 (Homo sapiens)	BDBM50481310 (CHEMBL603211) Show SMILES Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(C#N)c(C)cc2o1 Show InChI InChI=1S/C24H19N3O3/c1-15-5-3-4-6-21(15)29-14-23(28)26-19-9-7-17(8-10-19)24-27-20-12-18(13-25)16(2)11-22(20)30-24/h3-12H,14H2,1-2H3,(H,26,28)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description inhibition of human CEPT assessed as cholesteryl ester transfer by fluorescence transfer assay				Bioorg Med Chem Lett 20: 346-9 (2010) Article DOI: 10.1016/j.bmcl.2009.10.099 BindingDB Entry DOI: 10.7270/Q2FJ2KKK
					More data for this Ligand-Target Pair