null

SMILES: COc1cc(cc(OC)c1OC)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key: InChIKey=RFHHKLHLLXMGOX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50481483 (CHEMBL589285) Show SMILES COc1cc(cc(OC)c1OC)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H38N2O4/c1-39-31-23-29(24-32(40-2)35(31)41-3)34(28-17-11-6-12-18-28)37-21-19-36(20-22-37)33(38)25-30(26-13-7-4-8-14-26)27-15-9-5-10-16-27/h4-18,23-24,30,34H,19-22,25H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neuromed Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method				Bioorg Med Chem Lett 20: 1378-83 (2010) Article DOI: 10.1016/j.bmcl.2010.01.008 BindingDB Entry DOI: 10.7270/Q2DJ5JDR
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit beta-1 (Homo sapiens)	BDBM50481483 (CHEMBL589285) Show SMILES COc1cc(cc(OC)c1OC)C(N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C35H38N2O4/c1-39-31-23-29(24-32(40-2)35(31)41-3)34(28-17-11-6-12-18-28)37-21-19-36(20-22-37)33(38)25-30(26-13-7-4-8-14-26)27-15-9-5-10-16-27/h4-18,23-24,30,34H,19-22,25H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Neuromed Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...				Bioorg Med Chem Lett 20: 1378-83 (2010) Article DOI: 10.1016/j.bmcl.2010.01.008 BindingDB Entry DOI: 10.7270/Q2DJ5JDR
					More data for this Ligand-Target Pair