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SMILES: Clc1cccc(C(N2CCN(CC2)C(=O)NC(c2ccccc2)c2ccccc2)c2ccccc2)c1Cl

InChI Key: InChIKey=JJWWPFHYFYVBMO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481491   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit beta-1


(Homo sapiens)		BDBM50481491
PNG
(CHEMBL597957)
Show SMILES Clc1cccc(C(N2CCN(CC2)C(=O)NC(c2ccccc2)c2ccccc2)c2ccccc2)c1Cl
Show InChI InChI=1S/C31H29Cl2N3O/c32-27-18-10-17-26(28(27)33)30(25-15-8-3-9-16-25)35-19-21-36(22-20-35)31(37)34-29(23-11-4-1-5-12-23)24-13-6-2-7-14-24/h1-18,29-30H,19-22H2,(H,34,37)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Neuromed Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...

Bioorg Med Chem Lett 20: 1378-83 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.008
BindingDB Entry DOI: 10.7270/Q2DJ5JDR
More data for this
Ligand-Target Pair