null

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]C([#6]-[#6]-[#6]-c1nccn1-[#6])([#6](-[#8])=O)[#6](-[#8])=O

InChI Key: InChIKey=UDIXHMSAFKDLEW-FENOTYGDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50481619 (CHEMBL591827) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]C([#6]-[#6]-[#6]-c1nccn1-[#6])([#6](-[#8])=O)[#6](-[#8])=O Show InChI InChI=1S/C25H38N2O4/c1-19(2)9-6-10-20(3)11-7-12-21(4)14-16-25(23(28)29,24(30)31)15-8-13-22-26-17-18-27(22)5/h9,11,14,17-18H,6-8,10,12-13,15-16H2,1-5H3,(H,28,29)(H,30,31)/b20-11+,21-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche de Gif-sur-Yvette Curated by ChEMBL					Assay Description Inhibition of human recombinant FTase by fluorescent-based assay				Bioorg Med Chem 18: 543-56 (2010) Article DOI: 10.1016/j.bmc.2009.12.017 BindingDB Entry DOI: 10.7270/Q2VM4G37
					More data for this Ligand-Target Pair