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BDBM50481624 CHEMBL585242

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#8]-[#6](=O)-[#6]-[#6](-[#8])=O

InChI Key: InChIKey=RLLUYKLHAUJSCD-XGGJEREUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481624   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha


(Homo sapiens (Human))
BDBM50481624
PNG
(CHEMBL585242)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#8]-[#6](=O)-[#6]-[#6](-[#8])=O
Show InChI InChI=1S/C18H28O4/c1-14(2)7-5-8-15(3)9-6-10-16(4)11-12-22-18(21)13-17(19)20/h7,9,11H,5-6,8,10,12-13H2,1-4H3,(H,19,20)/b15-9+,16-11+
PDB
MMDB

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KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60E+5n/an/an/an/an/an/a



Centre de Recherche de Gif-sur-Yvette

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FTase by fluorescent-based assay


Bioorg Med Chem 18: 543-56 (2010)


Article DOI: 10.1016/j.bmc.2009.12.017
BindingDB Entry DOI: 10.7270/Q2VM4G37
More data for this
Ligand-Target Pair