BDBM50482071 CHEMBL1091178
SMILES: CC(CNC(=O)c1ccccc1O)\N=C\c1cc(Br)cc(Br)c1O
InChI Key: InChIKey=AHXIYODCAXTIKX-AWQFTUOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-ketoacyl-ACP synthase III (FabH) (Escherichia coli) | BDBM50482071![]() (CHEMBL1091178) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing University Curated by ChEMBL | Assay Description Inhibition of Escherichia coli KAS3 after 1 min assessed as incorporation of 3H signal in the final product by liquid scintillation counter | Bioorg Med Chem 18: 2447-55 (2010) Article DOI: 10.1016/j.bmc.2010.02.052 BindingDB Entry DOI: 10.7270/Q2H70JNT | |||||||||||
More data for this Ligand-Target Pair |