null

SMILES: CCOC(=O)C(\O)=C\C(=O)c1cn(Cc2ccccc2Cl)c2cccc(OC)c12

InChI Key: InChIKey=FGYRHGAPMDJCSK-ODLFYWEKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50482543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50482543 (CHEMBL1214417) Show SMILES CCOC(=O)C(\O)=C\C(=O)c1cn(Cc2ccccc2Cl)c2cccc(OC)c12 Show InChI InChI=1S/C22H20ClNO5/c1-3-29-22(27)19(26)11-18(25)15-13-24(12-14-7-4-5-8-16(14)23)17-9-6-10-20(28-2)21(15)17/h4-11,13,26H,3,12H2,1-2H3/b19-11-	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase strand transfer				Bioorg Med Chem 18: 5510-8 (2010) Article DOI: 10.1016/j.bmc.2010.06.063 BindingDB Entry DOI: 10.7270/Q2Z322G6
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50482543 (CHEMBL1214417) Show SMILES CCOC(=O)C(\O)=C\C(=O)c1cn(Cc2ccccc2Cl)c2cccc(OC)c12 Show InChI InChI=1S/C22H20ClNO5/c1-3-29-22(27)19(26)11-18(25)15-13-24(12-14-7-4-5-8-16(14)23)17-9-6-10-20(28-2)21(15)17/h4-11,13,26H,3,12H2,1-2H3/b19-11-	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase				Bioorg Med Chem 18: 5510-8 (2010) Article DOI: 10.1016/j.bmc.2010.06.063 BindingDB Entry DOI: 10.7270/Q2Z322G6
					More data for this Ligand-Target Pair