BDBM50483004 CHEMBL1270345

SMILES: Fc1cccc(-c2ccccc2)c1Nc1nc(Cl)nc(NCc2ccc3occc3c2)n1

InChI Key: InChIKey=SPXNACLKEBXSPI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483004   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483004 (CHEMBL1270345) Show SMILES Fc1cccc(-c2ccccc2)c1Nc1nc(Cl)nc(NCc2ccc3occc3c2)n1 Show InChI InChI=1S/C24H17ClFN5O/c25-22-29-23(27-14-15-9-10-20-17(13-15)11-12-32-20)31-24(30-22)28-21-18(7-4-8-19(21)26)16-5-2-1-3-6-16/h1-13H,14H2,(H2,27,28,29,30,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ansaris Curated by ChEMBL					Assay Description Inhibition of wild type HIV1 reverse transcriptase				Bioorg Med Chem Lett 20: 6592-6 (2010) Article DOI: 10.1016/j.bmcl.2010.09.034 BindingDB Entry DOI: 10.7270/Q2NG4TG2
					More data for this Ligand-Target Pair