BDBM50483010 CHEMBL1271044

SMILES: CC(C)(Nc1nc(O)nc(Nc2c(F)cccc2-c2ccccc2)n1)c1ccc2OCOc2c1

InChI Key: InChIKey=HKZCZABFVBDRKA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483010 (CHEMBL1271044) Show SMILES CC(C)(Nc1nc(O)nc(Nc2c(F)cccc2-c2ccccc2)n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C25H22FN5O3/c1-25(2,16-11-12-19-20(13-16)34-14-33-19)31-23-28-22(29-24(32)30-23)27-21-17(9-6-10-18(21)26)15-7-4-3-5-8-15/h3-13H,14H2,1-2H3,(H3,27,28,29,30,31,32)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ansaris Curated by ChEMBL					Assay Description Inhibition of wild type HIV1 reverse transcriptase				Bioorg Med Chem Lett 20: 6592-6 (2010) Article DOI: 10.1016/j.bmcl.2010.09.034 BindingDB Entry DOI: 10.7270/Q2NG4TG2
					More data for this Ligand-Target Pair