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SMILES: CC(OC(=O)N(C)c1ccccc1)c1sc2ncnn2c1C

InChI Key: InChIKey=IEKLDABYSCMDOV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483165   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50483165
PNG
(CHEMBL1630074)
Show SMILES CC(OC(=O)N(C)c1ccccc1)c1sc2ncnn2c1C
Show InChI InChI=1S/C15H16N4O2S/c1-10-13(22-14-16-9-17-19(10)14)11(2)21-15(20)18(3)12-7-5-4-6-8-12/h4-9,11H,1-3H3
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PC cid
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Article
PubMed
n/an/a<3.16E+4n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization

Bioorg Med Chem Lett 20: 7521-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.120
BindingDB Entry DOI: 10.7270/Q2KH0R5D
More data for this
Ligand-Target Pair