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SMILES: CNc1ccc(cc1)-c1cn2c(n1)sc1cc(OC)ccc21

InChI Key: InChIKey=ZSLILWZEKOAVKQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50483423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50483423 (CHEMBL1671878) Show SMILES CNc1ccc(cc1)-c1cn2c(n1)sc1cc(OC)ccc21 Show InChI InChI=1S/C17H15N3OS/c1-18-12-5-3-11(4-6-12)14-10-20-15-8-7-13(21-2)9-16(15)22-17(20)19-14/h3-10,18H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t M£nchen Curated by ChEMBL					Assay Description Displacement of [3H]PiB from human amyloid beta (1-40) at 100 nM after 180 mins by liquid scintillation counter				J Med Chem 54: 949-56 (2011) Article DOI: 10.1021/jm101129a BindingDB Entry DOI: 10.7270/Q2639SJM
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50483423 (CHEMBL1671878) Show SMILES CNc1ccc(cc1)-c1cn2c(n1)sc1cc(OC)ccc21 Show InChI InChI=1S/C17H15N3OS/c1-18-12-5-3-11(4-6-12)14-10-20-15-8-7-13(21-2)9-16(15)22-17(20)19-14/h3-10,18H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t M£nchen Curated by ChEMBL					Assay Description Displacement of [3H]PiB from human amyloid beta (1-42) at 100 nM after 180 mins by liquid scintillation counter				J Med Chem 54: 949-56 (2011) Article DOI: 10.1021/jm101129a BindingDB Entry DOI: 10.7270/Q2639SJM
					More data for this Ligand-Target Pair