BDBM50483465 CHEMBL1684737

SMILES: O=c1c(N2CCOCC2)c(cnn1-c1ccccc1)N1CCN(CC1)S(=O)(=O)Cc1ccccc1

InChI Key: InChIKey=PZXJUKQCRGDEMC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50483465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1,3-glucan synthase (Candida albicans)	BDBM50483465 (CHEMBL1684737) Show SMILES O=c1c(N2CCOCC2)c(cnn1-c1ccccc1)N1CCN(CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C25H29N5O4S/c31-25-24(28-15-17-34-18-16-28)23(19-26-30(25)22-9-5-2-6-10-22)27-11-13-29(14-12-27)35(32,33)20-21-7-3-1-4-8-21/h1-10,19H,11-18,20H2	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes				Bioorg Med Chem Lett 22: 5268-71 (2012) Article DOI: 10.1016/j.bmcl.2012.06.091 BindingDB Entry DOI: 10.7270/Q2MC92WW
					More data for this Ligand-Target Pair
Beta-1,3-glucan synthase (Candida albicans)	BDBM50483465 (CHEMBL1684737) Show SMILES O=c1c(N2CCOCC2)c(cnn1-c1ccccc1)N1CCN(CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C25H29N5O4S/c31-25-24(28-15-17-34-18-16-28)23(19-26-30(25)22-9-5-2-6-10-22)27-11-13-29(14-12-27)35(32,33)20-21-7-3-1-4-8-21/h1-10,19H,11-18,20H2	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Candida albicans BWP17 1,3-beta-D-glucan synthase				Bioorg Med Chem Lett 21: 1819-22 (2011) Article DOI: 10.1016/j.bmcl.2011.01.058 BindingDB Entry DOI: 10.7270/Q2P55RCG
					More data for this Ligand-Target Pair