BDBM50483614 CHEMBL1760910

SMILES: ONC(=O)CCCC1CCN(CC1)S(=O)(=O)Cc1ccccc1

InChI Key: InChIKey=NBRPFYMLOZGWRR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50483614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50483614 (CHEMBL1760910) Show SMILES ONC(=O)CCCC1CCN(CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C16H24N2O4S/c19-16(17-20)8-4-7-14-9-11-18(12-10-14)23(21,22)13-15-5-2-1-3-6-15/h1-3,5-6,14,20H,4,7-13H2,(H,17,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Pomezia Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cell extract assessed as fluorophore release by fluorescence spectrophotometry				Bioorg Med Chem Lett 21: 6767-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.042 BindingDB Entry DOI: 10.7270/Q2G44T34
					More data for this Ligand-Target Pair
Histone deacetylase (Homo sapiens (Human))	BDBM50483614 (CHEMBL1760910) Show SMILES ONC(=O)CCCC1CCN(CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C16H24N2O4S/c19-16(17-20)8-4-7-14-9-11-18(12-10-14)23(21,22)13-15-5-2-1-3-6-15/h1-3,5-6,14,20H,4,7-13H2,(H,17,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Pomezia Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells by fluorescent activity assay				Bioorg Med Chem Lett 21: 2305-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.085 BindingDB Entry DOI: 10.7270/Q2VQ35HJ
					More data for this Ligand-Target Pair