BDBM50483685 CHEMBL1766224

SMILES: Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCc1ccccc1

InChI Key: InChIKey=OSEJQKRMCRXNGM-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50483685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50483685 (CHEMBL1766224) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H20ClFN2O3S/c1-14-10-15(2)12-17(11-14)32(30,31)23-20-19(9-8-18(25)21(20)26)28-22(23)24(29)27-13-16-6-4-3-5-7-16/h3-12,28H,13H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase L100I mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483685 (CHEMBL1766224) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H20ClFN2O3S/c1-14-10-15(2)12-17(11-14)32(30,31)23-20-19(9-8-18(25)21(20)26)28-22(23)24(29)27-13-16-6-4-3-5-7-16/h3-12,28H,13H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181I mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483685 (CHEMBL1766224) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H20ClFN2O3S/c1-14-10-15(2)12-17(11-14)32(30,31)23-20-19(9-8-18(25)21(20)26)28-22(23)24(29)27-13-16-6-4-3-5-7-16/h3-12,28H,13H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50483685 (CHEMBL1766224) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)c(F)c12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C24H20ClFN2O3S/c1-14-10-15(2)12-17(11-14)32(30,31)23-20-19(9-8-18(25)21(20)26)28-22(23)24(29)27-13-16-6-4-3-5-7-16/h3-12,28H,13H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair