null

SMILES: Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCCOc1ccccc1

InChI Key: InChIKey=QGKHITXMFVWSAW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50483704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50483704 (CHEMBL1766242) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCCOc1ccccc1 Show InChI InChI=1S/C25H23BrN2O4S/c1-16-12-17(2)14-20(13-16)33(30,31)24-21-15-18(26)8-9-22(21)28-23(24)25(29)27-10-11-32-19-6-4-3-5-7-19/h3-9,12-15,28H,10-11H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50483704 (CHEMBL1766242) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCCOc1ccccc1 Show InChI InChI=1S/C25H23BrN2O4S/c1-16-12-17(2)14-20(13-16)33(30,31)24-21-15-18(26)8-9-22(21)28-23(24)25(29)27-10-11-32-19-6-4-3-5-7-19/h3-9,12-15,28H,10-11H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase L100I mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483704 (CHEMBL1766242) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCCOc1ccccc1 Show InChI InChI=1S/C25H23BrN2O4S/c1-16-12-17(2)14-20(13-16)33(30,31)24-21-15-18(26)8-9-22(21)28-23(24)25(29)27-10-11-32-19-6-4-3-5-7-19/h3-9,12-15,28H,10-11H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483704 (CHEMBL1766242) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Br)cc12)C(=O)NCCOc1ccccc1 Show InChI InChI=1S/C25H23BrN2O4S/c1-16-12-17(2)14-20(13-16)33(30,31)24-21-15-18(26)8-9-22(21)28-23(24)25(29)27-10-11-32-19-6-4-3-5-7-19/h3-9,12-15,28H,10-11H2,1-2H3,(H,27,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181I mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair