null

SMILES: Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCN1CCOCC1

InChI Key: InChIKey=YPIUHVHEJAWBSX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50483706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483706 (CHEMBL1766217) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCN1CCOCC1 Show InChI InChI=1S/C22H24ClN3O4S/c1-14-9-15(2)11-17(10-14)31(28,29)21-18-12-16(23)3-4-19(18)25-20(21)22(27)24-13-26-5-7-30-8-6-26/h3-4,9-12,25H,5-8,13H2,1-2H3,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181I mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50483706 (CHEMBL1766217) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCN1CCOCC1 Show InChI InChI=1S/C22H24ClN3O4S/c1-14-9-15(2)11-17(10-14)31(28,29)21-18-12-16(23)3-4-19(18)25-20(21)22(27)24-13-26-5-7-30-8-6-26/h3-4,9-12,25H,5-8,13H2,1-2H3,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	512	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50483706 (CHEMBL1766217) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCN1CCOCC1 Show InChI InChI=1S/C22H24ClN3O4S/c1-14-9-15(2)11-17(10-14)31(28,29)21-18-12-16(23)3-4-19(18)25-20(21)22(27)24-13-26-5-7-30-8-6-26/h3-4,9-12,25H,5-8,13H2,1-2H3,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase L100I mutant expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by ...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50483706 (CHEMBL1766217) Show SMILES Cc1cc(C)cc(c1)S(=O)(=O)c1c([nH]c2ccc(Cl)cc12)C(=O)NCN1CCOCC1 Show InChI InChI=1S/C22H24ClN3O4S/c1-14-9-15(2)11-17(10-14)31(28,29)21-18-12-16(23)3-4-19(18)25-20(21)22(27)24-13-26-5-7-30-8-6-26/h3-4,9-12,25H,5-8,13H2,1-2H3,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of HIV1 wild type reverse transcriptase expressed in Escherichia coli assessed as incorporation of [3H]dTTP into poly(rA)/oligo(dT) by sci...				J Med Chem 54: 1587-98 (2011) Article DOI: 10.1021/jm101614j BindingDB Entry DOI: 10.7270/Q2ZG6W3H
					More data for this Ligand-Target Pair