BindingDB logo
myBDB logout

null

SMILES: [H][C@@]1(CCc2c(C1)c(C)cc(O)c(=O)c2O)C(C)(O)CN1CCCCC1

InChI Key: InChIKey=ZUDNUZLSSFQSMM-PVCZSOGJSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484005   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50484005
PNG
(CHEMBL1802032)
Show SMILES [H][C@@]1(CCc2c(C1)c(C)cc(O)c(=O)c2O)C(C)(O)CN1CCCCC1 |r|
Show InChI InChI=1S/C20H29NO4/c1-13-10-17(22)19(24)18(23)15-7-6-14(11-16(13)15)20(2,25)12-21-8-4-3-5-9-21/h10,14,25H,3-9,11-12H2,1-2H3,(H2,22,23,24)/t14-,20?/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 820n/an/an/an/an/an/a



National Cancer Institute-Frederick

Curated by ChEMBL


Assay Description
Inhibition of RNase H activity of his6-tagged HIV1 HXB2 reverse transcriptase p66/p51 expressed in Escherichia coli assessed as substrate cleavage at...

J Med Chem 54: 4462-73 (2011)


Article DOI: 10.1021/jm2000757
BindingDB Entry DOI: 10.7270/Q26T0QH5
More data for this
Ligand-Target Pair