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BDBM50484333 CHEMBL1835516

SMILES: Cc1cc(C)cc(c1)C(O)c1cc(Cl)ccc1OCCn1ccc(=O)[nH]c1=O

InChI Key: InChIKey=NNTQIAILNOMATN-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484333   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50484333
PNG
(CHEMBL1835516)
Show SMILES Cc1cc(C)cc(c1)C(O)c1cc(Cl)ccc1OCCn1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C21H21ClN2O4/c1-13-9-14(2)11-15(10-13)20(26)17-12-16(22)3-4-18(17)28-8-7-24-6-5-19(25)23-21(24)27/h3-6,9-12,20,26H,7-8H2,1-2H3,(H,23,25,27)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>2.49E+5n/an/an/an/an/an/an/an/a



Volgograd State Medical University

Curated by ChEMBL


Assay Description
Inhibition of RNA-dependent DNA polymerase activity of HIV1 reverse transcriptase p66/p51 heterodimer using [8-3H]dGTP as substrate after 30 mins by ...

Bioorg Med Chem 19: 5794-802 (2011)


Article DOI: 10.1016/j.bmc.2011.08.025
BindingDB Entry DOI: 10.7270/Q2057JRG
More data for this
Ligand-Target Pair