BDBM50484408 CHEMBL1915827

SMILES: COc1cc(OC)cc(c1)C(=C/C#N)\c1ccc(OC)c(OC)c1

InChI Key: InChIKey=QNZGJJKAOJFFSP-IDUWFGFVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50484408 (CHEMBL1915827) Show SMILES COc1cc(OC)cc(c1)C(=C/C#N)\c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H19NO4/c1-21-15-9-14(10-16(12-15)22-2)17(7-8-20)13-5-6-18(23-3)19(11-13)24-4/h5-7,9-12H,1-4H3/b17-7-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4 expressed in U937 cells using [3H]cAMP as substrate after 30 mins				Bioorg Med Chem 19: 6356-74 (2011) Article DOI: 10.1016/j.bmc.2011.08.068 BindingDB Entry DOI: 10.7270/Q2Z60RXK
					More data for this Ligand-Target Pair