BDBM50484425 CHEMBL1916067

SMILES: CCOc1cc(ccc1OC)C(=C)c1ccc(OC)c(O)c1

InChI Key: InChIKey=DGMJDCGCTRGAHL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50484425 (CHEMBL1916067) Show SMILES CCOc1cc(ccc1OC)C(=C)c1ccc(OC)c(O)c1 Show InChI InChI=1S/C18H20O4/c1-5-22-18-11-14(7-9-17(18)21-4)12(2)13-6-8-16(20-3)15(19)10-13/h6-11,19H,2,5H2,1,3-4H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4 expressed in U937 cells using [3H]cAMP as substrate after 30 mins				Bioorg Med Chem 19: 6356-74 (2011) Article DOI: 10.1016/j.bmc.2011.08.068 BindingDB Entry DOI: 10.7270/Q2Z60RXK
					More data for this Ligand-Target Pair