BDBM50484444 3,3-Bis(3,4,5-Trimethoxyphenyl)Acrylonitrile::CHEMBL1915830

SMILES: [#6]-[#8]-c1cc(cc(-[#8]-[#6])c1-[#8]-[#6])-[#6](=[#6]\C#N)\c1cc(-[#8]-[#6])c(-[#8]-[#6])c(-[#8]-[#6])c1

InChI Key: InChIKey=FRUSWTFAJIAFQZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50484444 (3,3-Bis(3,4,5-Trimethoxyphenyl)Acrylonitrile | CHE...) Show SMILES [#6]-[#8]-c1cc(cc(-[#8]-[#6])c1-[#8]-[#6])-[#6](=[#6]\C#N)\c1cc(-[#8]-[#6])c(-[#8]-[#6])c(-[#8]-[#6])c1 Show InChI InChI=1S/C21H23NO6/c1-23-16-9-13(10-17(24-2)20(16)27-5)15(7-8-22)14-11-18(25-3)21(28-6)19(12-14)26-4/h7,9-12H,1-6H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4 expressed in U937 cells using [3H]cAMP as substrate after 30 mins				Bioorg Med Chem 19: 6356-74 (2011) Article DOI: 10.1016/j.bmc.2011.08.068 BindingDB Entry DOI: 10.7270/Q2Z60RXK
					More data for this Ligand-Target Pair