BDBM50484492 CHEMBL1928643
SMILES: Cc1ccn(Cc2n[nH]c3ncccc23)c(=O)c1Oc1cc(Cl)cc(c1)C#N
InChI Key: InChIKey=YMRUCOCNLHJFRC-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse Transcriptase (Human immunodeficiency virus 1) | BDBM50484492 (CHEMBL1928643) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Labs. Curated by ChEMBL | Assay Description Inhibition of Human immunodeficiency virus reverse transcriptase K103N mutant by SPA assay | Bioorg Med Chem Lett 21: 7344-50 (2011) Article DOI: 10.1016/j.bmcl.2011.10.027 BindingDB Entry DOI: 10.7270/Q25Q4ZZ2 | |||||||||||
More data for this Ligand-Target Pair |