BindingDB logo
myBDB logout

null

SMILES: ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)Nc1cccc(F)c1

InChI Key: InChIKey=VCSWVYSDADYKCT-BQYQJAHWSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484757   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase


(Homo sapiens (Human))		BDBM50484757
PNG
(CHEMBL1958436)
Show SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)Nc1cccc(F)c1
Show InChI InChI=1S/C15H13FN2O4S/c16-12-4-2-5-13(10-12)18-23(21,22)14-6-1-3-11(9-14)7-8-15(19)17-20/h1-10,18,20H,(H,17,19)/b8-7+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



London School of Hygiene and Tropical Medicine

Curated by ChEMBL


Assay Description
Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysis

Bioorg Med Chem Lett 22: 1886-90 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.072
BindingDB Entry DOI: 10.7270/Q2QF8WQT
More data for this
Ligand-Target Pair