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SMILES: ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)N1CCN(CC1)c1ccccc1

InChI Key: InChIKey=CBKGZQAVXZQSHA-MDZDMXLPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484763   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase


(Homo sapiens (Human))		BDBM50484763
PNG
(CHEMBL1958432)
Show SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C19H21N3O4S/c23-19(20-24)10-9-16-5-4-8-18(15-16)27(25,26)22-13-11-21(12-14-22)17-6-2-1-3-7-17/h1-10,15,24H,11-14H2,(H,20,23)/b10-9+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 132n/an/an/an/an/an/a



London School of Hygiene and Tropical Medicine

Curated by ChEMBL


Assay Description
Inhibition of HDAC expressed in human HeLa cells after 1 hr by fluorescence analysis

Bioorg Med Chem Lett 22: 1886-90 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.072
BindingDB Entry DOI: 10.7270/Q2QF8WQT
More data for this
Ligand-Target Pair