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SMILES: Fc1cc(F)cc(Cc2c(I)c(=O)[nH]c(=O)n2COCc2ccccc2)c1

InChI Key: InChIKey=OXSVGZCCNVYPAP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485250   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50485250
PNG
(CHEMBL2041784)
Show SMILES Fc1cc(F)cc(Cc2c(I)c(=O)[nH]c(=O)n2COCc2ccccc2)c1
Show InChI InChI=1S/C19H15F2IN2O3/c20-14-6-13(7-15(21)9-14)8-16-17(22)18(25)23-19(26)24(16)11-27-10-12-4-2-1-3-5-12/h1-7,9H,8,10-11H2,(H,23,25,26)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Peking University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase using poly(ra)/oligo(dT)15 homopolymer template as substrate after 1 hr

J Med Chem 55: 2242-50 (2012)


Article DOI: 10.1021/jm201506e
BindingDB Entry DOI: 10.7270/Q22N554J
More data for this
Ligand-Target Pair