BDBM50485337 CHEMBL2046737

SMILES: CC1(CO\C(C(=O)Nc2cccc(Cl)c2)=C(\C=N)N2CCN(CC2)S(=O)(=O)NCc2cccnc2)CC1

InChI Key: InChIKey=FONVZDXRRXHSMH-JQULFPKWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1,3-glucan synthase (Candida albicans)	BDBM50485337 (CHEMBL2046737) Show SMILES CC1(CO\C(C(=O)Nc2cccc(Cl)c2)=C(\C=N)N2CCN(CC2)S(=O)(=O)NCc2cccnc2)CC1 Show InChI InChI=1S/C25H31ClN6O4S/c1-25(7-8-25)18-36-23(24(33)30-21-6-2-5-20(26)14-21)22(15-27)31-10-12-32(13-11-31)37(34,35)29-17-19-4-3-9-28-16-19/h2-6,9,14-16,27,29H,7-8,10-13,17-18H2,1H3,(H,30,33)/b23-22-,27-15?	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	201	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research, Inc. (AMRI) Curated by ChEMBL					Assay Description Inhibition of glucan synthase in Candida albicans BWP17 membrane				Bioorg Med Chem Lett 22: 4896-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.127 BindingDB Entry DOI: 10.7270/Q2NC6424
					More data for this Ligand-Target Pair