BDBM50485383 CHEMBL2059477

SMILES: CC(C)(O)CCOc1c(cnn(-c2cc(F)cc(F)c2)c1=O)N1CCN(CC1)S(=O)(=O)Cc1ccccc1

InChI Key: InChIKey=UOIYCOGGABDQKV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1,3-glucan synthase (Candida albicans)	BDBM50485383 (CHEMBL2059477) Show SMILES CC(C)(O)CCOc1c(cnn(-c2cc(F)cc(F)c2)c1=O)N1CCN(CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C26H30F2N4O5S/c1-26(2,34)8-13-37-24-23(17-29-32(25(24)33)22-15-20(27)14-21(28)16-22)30-9-11-31(12-10-30)38(35,36)18-19-6-4-3-5-7-19/h3-7,14-17,34H,8-13,18H2,1-2H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	565	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes				Bioorg Med Chem Lett 22: 5268-71 (2012) Article DOI: 10.1016/j.bmcl.2012.06.091 BindingDB Entry DOI: 10.7270/Q2MC92WW
					More data for this Ligand-Target Pair