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SMILES: F[P-](F)(F)(F)(F)F.[#6]C([#6])([#6])c1cc(cc([se;v3+]1)C([#6])([#6])[#6])-c1ccc(s1)-[#6](-[#8])=O

InChI Key: InChIKey=VEXJDWZFMIULKR-UHFFFAOYSA-O

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485629   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50485629
PNG
(CHEMBL2087763)
Show SMILES F[P-](F)(F)(F)(F)F.[#6]C([#6])([#6])c1cc(cc([se;v3+]1)C([#6])([#6])[#6])-c1ccc(s1)-[#6](-[#8])=O
Show InChI InChI=1S/C18H22O2SSe/c1-17(2,3)14-9-11(10-15(22-14)18(4,5)6)12-7-8-13(21-12)16(19)20/h7-10H,1-6H3/p+1
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.11E+5n/an/an/an/an/an/a



The State University of New York

Curated by ChEMBL


Assay Description
Inhibition of VER-stimulated human His10-tagged P-gp ATPase activity expressed in BHK cells after 15 mins

J Med Chem 55: 4683-99 (2012)


Article DOI: 10.1021/jm3004398
BindingDB Entry DOI: 10.7270/Q2057JSX
More data for this
Ligand-Target Pair