BDBM50485631 CHEMBL2088335
SMILES: Cc1cc(C)c(c(C)c1)-n1c(SCC(=O)Nc2ccc(cc2Br)S(N)(=O)=O)nc2cnccc12
InChI Key: InChIKey=XVVJIPXKHZXJMX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50485631 (CHEMBL2088335) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shandong University Curated by ChEMBL | Assay Description Inhibition of recombinant HIV-1 RT assessed as inhibition of biotin-dUTP incorporation by colorimetric analysis | Bioorg Med Chem 20: 5527-36 (2012) Article DOI: 10.1016/j.bmc.2012.07.026 BindingDB Entry DOI: 10.7270/Q2QR511G | |||||||||||
More data for this Ligand-Target Pair |