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SMILES: ONC(=O)CCCCCCCC(=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=TWOKKEAKHUBCEZ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50486568   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 8


(Homo sapiens (Human))		BDBM50486568
PNG
(CHEMBL2235258)
Show SMILES ONC(=O)CCCCCCCC(=O)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C16H20F3NO3/c17-16(18,19)13-10-8-12(9-11-13)14(21)6-4-2-1-3-5-7-15(22)20-23/h8-11,23H,1-7H2,(H,20,22)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem
Article
n/an/a 45n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Homo sapiens (human) HDAC8

Citation and Details

Article DOI: 10.1007/s00044-011-9571-y
BindingDB Entry DOI: 10.7270/Q2KH0R79
More data for this
Ligand-Target Pair