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SMILES: COc1ccc(CS(=O)(=O)Nc2ccc(\C=C/C(=O)NO)cc2)cc1

InChI Key: InChIKey=RCJMLKKMXBTAQO-WDZFZDKYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50486586   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 8


(Homo sapiens (Human))		BDBM50486586
PNG
(CHEMBL2235664)
Show SMILES COc1ccc(CS(=O)(=O)Nc2ccc(\C=C/C(=O)NO)cc2)cc1
Show InChI InChI=1S/C17H18N2O5S/c1-24-16-9-4-14(5-10-16)12-25(22,23)19-15-7-2-13(3-8-15)6-11-17(20)18-21/h2-11,19,21H,12H2,1H3,(H,18,20)/b11-6-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a 60n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Homo sapiens (human) HDAC8

Citation and Details

Article DOI: 10.1007/s00044-011-9571-y
BindingDB Entry DOI: 10.7270/Q2KH0R79
More data for this
Ligand-Target Pair