null

SMILES: CC(C)C[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1

InChI Key: InChIKey=HGRMYMRCAGWXEQ-SFHVURJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50488804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50488804 (CHEMBL2295950) Show SMILES CC(C)C[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C23H28N8O/c1-14(2)12-18(32)28-23-29-21(19-22(30-23)31(13-26-19)15(3)4)27-17-8-6-16(7-9-17)20-24-10-5-11-25-20/h5-11,13-15,18,32H,12H2,1-4H3,(H2,27,28,29,30)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant CDK2/cyclin A using histone H1 and [gamma33P]ATP as substrate after 30 min by scintillation counting				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta/[Tau protein] kinase (Sus scrofa)	BDBM50488804 (CHEMBL2295950) Show SMILES CC(C)C[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C23H28N8O/c1-14(2)12-18(32)28-23-29-21(19-22(30-23)31(13-26-19)15(3)4)27-17-8-6-16(7-9-17)20-24-10-5-11-25-20/h5-11,13-15,18,32H,12H2,1-4H3,(H2,27,28,29,30)/t18-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Sus scrofa (pig) glycogen synthase kinase 3alpha/beta isolated from brain using YRRAAVPPSPSLSRHSSPHQpSEDEEE and [gamma33P]ATP as substr...				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair
Casein kinase 1, delta tv1 (Sus scrofa)	BDBM50488804 (CHEMBL2295950) Show SMILES CC(C)C[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C23H28N8O/c1-14(2)12-18(32)28-23-29-21(19-22(30-23)31(13-26-19)15(3)4)27-17-8-6-16(7-9-17)20-24-10-5-11-25-20/h5-11,13-15,18,32H,12H2,1-4H3,(H2,27,28,29,30)/t18-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Sus scrofa (pig) casein kinase 1delta/epsilon isolated from brain using RRKHAAIGpSAYSITA and [gamma33P]ATP as substrate after 30 min by...				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50488804 (CHEMBL2295950) Show SMILES CC(C)C[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C23H28N8O/c1-14(2)12-18(32)28-23-29-21(19-22(30-23)31(13-26-19)15(3)4)27-17-8-6-16(7-9-17)20-24-10-5-11-25-20/h5-11,13-15,18,32H,12H2,1-4H3,(H2,27,28,29,30)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Homo sapiens (human) recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ and [gamma33P]ATP as substrate af...				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50488804 (CHEMBL2295950) Show SMILES CC(C)C[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C23H28N8O/c1-14(2)12-18(32)28-23-29-21(19-22(30-23)31(13-26-19)15(3)4)27-17-8-6-16(7-9-17)20-24-10-5-11-25-20/h5-11,13-15,18,32H,12H2,1-4H3,(H2,27,28,29,30)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [gamma33P]ATP as substrate after 30 min by scintillation counting				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair