BDBM50488809 CHEMBL2295947
SMILES: CCC[C@@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1
InChI Key: InChIKey=PBTNYNHOVGFGNO-QGZVFWFLSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Casein kinase 1, delta tv1 (Sus scrofa) | BDBM50488809 (CHEMBL2295947) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Sus scrofa (pig) casein kinase 1delta/epsilon isolated from brain using RRKHAAIGpSAYSITA and [gamma33P]ATP as substrate after 30 min by... | Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta/[Tau protein] kinase (Sus scrofa) | BDBM50488809 (CHEMBL2295947) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Sus scrofa (pig) glycogen synthase kinase 3alpha/beta isolated from brain using YRRAAVPPSPSLSRHSSPHQpSEDEEE and [gamma33P]ATP as substr... | Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human)) | BDBM50488809 (CHEMBL2295947) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [gamma33P]ATP as substrate after 30 min by scintillation counting | Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G2/mitotic-specific cyclin-B (Asterina pectinifera) | BDBM50488809 (CHEMBL2295947) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ... | Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F | |||||||||||
More data for this Ligand-Target Pair |