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SMILES: CO\N=C(/C)c1ccc2c(ccc(OC)c2n1)C(=O)Nc1c(Cl)cncc1Cl

InChI Key: InChIKey=JVZRSLGGZJREPI-KIBLKLHPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50489034   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50489034
PNG
(CHEMBL2298606)
Show SMILES CO\N=C(/C)c1ccc2c(ccc(OC)c2n1)C(=O)Nc1c(Cl)cncc1Cl
Show InChI InChI=1S/C19H16Cl2N4O3/c1-10(25-28-3)15-6-4-11-12(5-7-16(27-2)17(11)23-15)19(26)24-18-13(20)8-22-9-14(18)21/h4-9H,1-3H3,(H,22,24,26)/b25-10+
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a 210n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of PDE4 in Homo sapiens (human) U937 cells

Citation and Details

Article DOI: 10.1007/s00044-012-0457-4
BindingDB Entry DOI: 10.7270/Q2CR5X7T
More data for this
Ligand-Target Pair