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SMILES: COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2n(C)cnc12

InChI Key: InChIKey=KMEZVOBKQOCLHX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50489035   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50489035
PNG
(CHEMBL289312)
Show SMILES COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2n(C)cnc12
Show InChI InChI=1S/C15H12Cl2N4O2/c1-21-7-19-13-11(23-2)4-3-8(14(13)21)15(22)20-12-9(16)5-18-6-10(12)17/h3-7H,1-2H3,(H,18,20,22)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
n/an/a 1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of PDE4 in Homo sapiens (human) U937 cells

Citation and Details

Article DOI: 10.1007/s00044-012-0457-4
BindingDB Entry DOI: 10.7270/Q2CR5X7T
More data for this
Ligand-Target Pair