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SMILES: Cn1c2cc(Cc3ccc(F)cc3)cnc2c(O)c(C(=O)NCC(F)F)c1=O

InChI Key: InChIKey=QFLCQXLLYBPIOP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50489266   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrase


(Human immunodeficiency virus 1)		BDBM50489266
PNG
(CHEMBL2316119)
Show SMILES Cn1c2cc(Cc3ccc(F)cc3)cnc2c(O)c(C(=O)NCC(F)F)c1=O
Show InChI InChI=1S/C19H16F3N3O3/c1-25-13-7-11(6-10-2-4-12(20)5-3-10)8-23-16(13)17(26)15(19(25)28)18(27)24-9-14(21)22/h2-5,7-8,14,26H,6,9H2,1H3,(H,24,27)
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



GlaxoSmithKline Research & Development

Curated by ChEMBL


Assay Description
Inhibition of HIV1 integrase strand transfer activity

Bioorg Med Chem Lett 23: 422-5 (2013)


Article DOI: 10.1016/j.bmcl.2012.11.071
BindingDB Entry DOI: 10.7270/Q2XK8JFB
More data for this
Ligand-Target Pair