BDBM50490521 CHEMBL2326615

SMILES: CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(cccc23)C(F)F)c1

InChI Key: InChIKey=FWDBCHHWAWMCFJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (Homo sapiens (Human))	BDBM50490521 (CHEMBL2326615) Show SMILES CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(cccc23)C(F)F)c1 Show InChI InChI=1S/C22H19ClF2N4O3S2/c1-13(30)26-11-14-4-2-5-15(10-14)12-29-17-7-3-6-16(21(24)25)20(17)22(27-29)28-34(31,32)19-9-8-18(23)33-19/h2-10,21H,11-12H2,1H3,(H,26,30)(H,27,28)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CCR4 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assay				J Med Chem 56: 1946-60 (2013) Article DOI: 10.1021/jm301572h BindingDB Entry DOI: 10.7270/Q26W9F07
					More data for this Ligand-Target Pair