BDBM50490698 CHEMBL2337683

SMILES: [Br-].CCCCc1n(Cc2ccc(cc2)-c2ccccc2-c2nn[nH]n2)c(CO)c[n+]1Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1

InChI Key: InChIKey=UOAKRJWAQBLEDF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50490698 (CHEMBL2337683) Show SMILES [Br-].CCCCc1n(Cc2ccc(cc2)-c2ccccc2-c2nn[nH]n2)c(CO)c[n+]1Cc1ccc(cc1)-c1ccccc1-c1nn[nH]n1 Show InChI InChI=1S/C36H35N10O/c1-2-3-12-34-45(21-25-13-17-27(18-14-25)30-8-4-6-10-32(30)35-37-41-42-38-35)23-29(24-47)46(34)22-26-15-19-28(20-16-26)31-9-5-7-11-33(31)36-39-43-44-40-36/h4-11,13-20,23,47H,2-3,12,21-22,24H2,1H3,(H,37,38,41,42)(H,39,40,43,44)/q+1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	417	n/a	n/a	n/a	n/a	n/a	n/a
University of Patras Curated by ChEMBL					Assay Description Displacement of [125I-Sar1-Ile8]-ANG2 from human Angiotensin 2 type-1 receptor expressed in HEK293 cells after 1 hr by gamma counting analysis				Eur J Med Chem 62: 352-70 (2013) Article DOI: 10.1016/j.ejmech.2012.12.044 BindingDB Entry DOI: 10.7270/Q2DF6V47
					More data for this Ligand-Target Pair